I’m talking about SM04554 but I’m also talking about Shisheido.
I understand that SM04554 may not work but I think that the greater
probability is that it does work. I’m aware of the rumors about SM04554 but
those rumors are not credible.
There is a rumor that there was no hair growth in the phase one study
They only applied the medicine a short time in the phase 1 study. I would be
surprised if it worked after applying it such a short amount of time. I think
it was applied for just 2 weeks or 10 days. Sure they said they would be
checking for hair growth but I do not think they truly intended that phase 1
study as an efficacy study. I think they were mostly assessing side effects
and toxicity after minimal application.
The rumors about phase 2 come from a couple of guys posting on the internet
who said they were just starting the study. One of them said he talked with
a nurse at the facility who said that she could not see any difference in any
of the patients to that point. This was a few months ago so the stydy was
about 7 or 8 months old. Assuming they weren’t trolls, when that guy posted
that information he was surely violating a nondisclosure agreement so that
shows that he’s willing to violate the nondisclosure agreement. But for some
reason he stopped posting. That seems odd to me.
Those are the rumors I’ve heard about. I do not find these rumors credible
and there are reasons to believe that the drug did work. For example, Samumed
only has one drug in their hair loss pipeline so if it failed in phase 2 it
seems to me that they would pull the plug on that one drug and close up
their hair project entirely after a phase 2 failure. I don’t think they would
waste millions of dollars on an extra phase 2 study. And Samumed is investing
resources getting involved in the coming Hair Loss Congress as a major sponsor.
Why would they do this if their only hair loss treatment in the pipeline is
a known failure?