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Brain growth linked to baldness...........BBC article


#1

Brain growth linked to baldness

The finding could lead to better hair loss treatments

Revolutionary hair loss treatments could be on the way after skin specialists found a link between a brain cell growth protein and the rate at which hair falls out.
The German scientists found that by increasing the body’s levels of brain growth proteins they also increased the rate at which hair falls out.

Restricting levels meant hair was shed at a slower rate.

The finding could lead to improved treatments to get rid of unwanted hair and for treating baldness, according to a report in New Scientist magazine.

Mousy hair

Dr Ralf Paus and colleagues carried out the research at Humbolt University in Berlin.

US experiments last year produced extremely hairy mice

They looked at growth cycles of hair follicles and their relationship with brain cell development.

Their earlier research showed that when mice lost hair, there was a high concentration of brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT-4) around their follicles.

BDNF and NT-4 are two growth factors thought to be important in the development of brain cells.

The earlier research also showed that the genes that make the proteins are abnormally active at the same time.

Balding from birth

For the new study, the team genetically-engineered mice to produce excess quantities of both the factors.

They found that the mice shed their hair abnormally early.

In mice engineered to produce neither factor, hair took longer than normal to fall out.

“This is the first evidence that growth factors previously thought to be important for the development of brain cells are also important for the growth of hair follicles,” Dr Paus told the magazine.

The scientists think the proteins work by binding to a receptor called tyrosine kinase B.

Treatments in development

Practical uses of the finding would be increasing the presence of BDNF and NT-4 around unwanted hair or using drugs to block the receptor to hold baldness at bay.

Such drugs have already been developed for use in diseases such as Alzheimer’s and multiple sclerosis, said Dr Paus.

“It’s not too far-fetched to propose using them for hair disorders, particularly if you can apply them topically in lotions,” he said.

However, it was too early to tell whether the findings in mice would apply to humans, he added.

This is because mice grow hair in synchronised waves whereas in humans each hair follicle grows independently.

File this under “God is an A$$hole”. Tyrosine kinease inhibitors for baldness is in a patent or two.


#2

» Brain growth linked to baldness

Hmmm…so does that mean that bald people are smarter? :stuck_out_tongue:


#3

Yea!!!Germany,we the best;-) But it dont help us now!!!:frowning:


#4

» Yea!!!Germany,we the best;-) But it dont help us now!!!:frowning:

what a stupid post stevi! :expressionless:

But an interesting article…


#5

» » Brain growth linked to baldness
»
» Hmmm…so does that mean that bald people are smarter? :stuck_out_tongue:

Have you read hanging’s comments?
Short answer. NOT ALWAYS.

.


#6

» » Yea!!!Germany,we the best;-) But it dont help us now!!!:frowning:
»
» what a stupid post stevi! :expressionless:
»

» But a interesting article…
Sorry…:frowning:


#7

» » » Yea!!!Germany,we the best;-) But it dont help us now!!!:frowning:
» »
» » what a stupid post stevi! :expressionless:
» »
»
» » But a interesting article…
» Sorry…:frowning:

Scientists are a rather balding lot…and there are alot of engineers and scientists in Germany. Mice that could complete mazes the fastest (the smartest ones) were shown to have more fur-loss earlier than contorl (duber mice). The Smad-7 pathway was shown to be a bit elevated in the smart mice if I rememeber correctly and it correlates to sebaceous gland hyperplasia and less fur.


#8

» Have you read hanging’s comments?
» Short answer. NOT ALWAYS.

true dat!


#9

More findings about mice, not people.


#10

Strangely enough, my conclusion runs a little different:

finasteride makes me dumb. One more side effect Merck Sharp has downplayed.
That would make a nice stastistic study, like:

2% users report increased dumbness which generally disappears after months of use. Maybe their smart word for it is brain fog.


#11

» » » Brain growth linked to baldness
» »
» » Hmmm…so does that mean that bald people are smarter? :stuck_out_tongue:
»
» Have you read hanging’s comments?
» Short answer. NOT ALWAYS.

:clap: :smiley: :lol2: :clap:


#12

» » » » Brain growth linked to baldness
» » »
» » » Hmmm…so does that mean that bald people are smarter? :stuck_out_tongue:
» »
» » Have you read hanging’s comments?
» » Short answer. NOT ALWAYS.
»
» :clap: :smiley: :lol2: :clap:

this is not widows…:rotfl:


#13

» » » Brain growth linked to baldness
» »
» » Hmmm…so does that mean that bald people are smarter? :stuck_out_tongue:
»
» Have you read hanging’s comments?
» Short answer. NOT ALWAYS.
»
»
»
» .

if the level of your baldness makes you smarter

Rev must be president of Mensa :lol2:


#14

Ok all this means, no thinking guys, from now on, we do not think, every new thing you learn, makes you more bald!!! STOP DOING THAT! :slight_smile:


#15


#16

» » » » » Brain growth linked to baldness
» » » »
» » » » Hmmm…so does that mean that bald people are smarter? :stuck_out_tongue:
» » »
» » » Have you read hanging’s comments?
» » » Short answer. NOT ALWAYS.
» »
» » :clap: :smiley: :lol2: :clap:
»
» hanging
» this is not widows…:
rotfl:

Replies like that merely debunk Benji’s link.

.


#17

» » » » » » Brain growth linked to baldness
» » » » »
» » » » » Hmmm…so does that mean that bald people are smarter? :stuck_out_tongue:
» » » »
» » » » Have you read hanging’s comments?
» » » » Short answer. NOT ALWAYS.
» » »
» » » :clap: :smiley: :lol2: :clap:
» »
» » hanging
» » this is not widows…:
rotfl:
»
»
» Replies like that merely debunk Benji’s link.
»
»
» .

every reply you make, …makes scientists wonder if only retards go bald


#18

» » » » » » » Brain growth linked to baldness
» » » » » »
» » » » » » Hmmm…so does that mean that bald people are smarter? :stuck_out_tongue:
» » » » »
» » » » » Have you read hanging’s comments?
» » » » » Short answer. NOT ALWAYS.
» » » »
» » » » :clap: :smiley: :lol2: :clap:
» » »
» » » hanging
» » » this is not widows…:
rotfl:
» »
» »
» » Replies like that merely debunk Benji’s link.
» »
» »
» » .
»
» every reply you make, …makes scientists wonder if only retards go
» bald

they have you on speed dial.

.


#19

what confirms you are pathetic

is your crying to everyone on the board about me in your sig

whats wrong, too weak to handle me on your own?

definitely :smiley: :smiley: :smiley: :smiley:


#20

There have always been serious doubts about Einstein’s paternity ot the theory of relativity. The guy seems to have published under his name results that were not his complete own.