I’ll restate my point about the two people who had a great deal of growth with getfitinib.
Both were taking the drug for cancer (its a cancer drug).
Both probably had compromised immune systems (chemo can suppress the immune system profoundly).
Lets go to the human skin series of experiments on SCID mice. Was a EGF-receptor blocker used? No. The depilated, waited three days, and abraded. Thats it. No getfitinib. What is the difference between human skin on a SCID mouse and human skin on you? You have a working immune system that will send cells to a wound and fight off any infection in the area and inflame it with various cells, attacking invading bacteria, fungi, parasites and whatever else is in the air that lights on the broken skin----where you are vunerable, just like it is supposed to do.
Follica may try this with just very strong anti-inflammatories and anti-histamines and anti-microbials and anti-bacterials topically applied with a EGF-antagonist and minoxidil. That may prove to be a winner because the immune systems travelling cells wont see much “amiss” and the foreign invaders that it seeks to destroy will not be in evidence in the area. Concievably one might be able to use an anti-histamine and ibuprofin (anti-inflammatory) along with egf inhibition.
The mice didn’t have any of those things though…they just had a suppressed immune system.
I have a feeling Follica, with two dermatological experts working for them, will be able to make this go without interdicting the immunity of a person topically or internally, but you’ll note they put that option in the patent. Maybe they dont want another entity to try it because they feel sure it would work, or maybe they included the immunosuppressants cyclo, rampycin, tacromilus, pinecromilus, and one other one because they knew if all else failed that they could indeed get growth if they resorted to this.
Sales of cyclosporin worldwide are 1 billion a year. Lots of people have to take it for a year or so. I really dont think 10 or 12 days of it (you might have to be on it for a couple of days before the wounding) would kill a healthy man or even compromise his health.
If someone put a gun to my head though and told me to get growth by any means possible, I’d say use getfitinib, internal cyclo, and internal loniten for ten full days after a 3 day wait after depilation before the wounding.
We must also keep in mind that there are other things buried in the patent like beta catenin, ectodysplasin, fgf, and a couple of other things that they might be screwing with…
The mind goes back to that human skin experiment and the getfitinib patients though. Weak immune systems, getfitinib. It made hair on someone’s freakin’ nose. Those two should be enough.
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