@Bald-HalfTruth - adreans trial?

Stem cell; cell based hair therapy
121

» » » I agree, all of these trials look very promising and optimistic. I
» think
» » » that within 3 to 5 years this should hit the market. Very
» » promising!
» »
» » Let’s say within the next 3 years. Maybe they’re not even forced by FDA
» to
» » do a phase III trail. YES, that COULD be possible too …
»
» yea… or maybe jesus’ second coming in june will bring hair to us all…
» that COULD BE too…
»
» also what exactly do you find so promising we hardly know anything about
» these trails

It always seems, YOU hardly know anything. So you can’t simply say “we” in this context. I, for example, do not need any discussion-forum-members like e.g. “BaldHalfTruth” or forum members like “mj2003” …
http://www.hairsite.com/hair-loss/board_entry-id-64827-page-0-category-1-order-last_answer-descasc-DESC.html

… if I wish to know anything about specific things called “facts”: There exists e.g. other forums, blogs, chats etc. AND - you won’t believe that - real persons and telephones for simple communication too - IF I’m not sure about specific things/facts. So PLEASE, especially guys like you, shouldn’t use “we” (trying to implicating “there are lots of others behind me too” ) in a specific context, who are always just wait for informations by others.

122

» » » » I agree, all of these trials look very promising and optimistic. I
» » think
» » » » that within 3 to 5 years this should hit the market. Very
» » » promising!
» » »
» » » Let’s say within the next 3 years. Maybe they’re not even forced by
» FDA
» » to
» » » do a phase III trail. YES, that COULD be possible too …
» »
» » yea… or maybe jesus’ second coming in june
» will bring hair to us all…
» » that COULD BE too…
» »
» » also what exactly do you find so promising we
» hardly know anything about
» » these trails
»
» It always seems, YOU hardly know anything. So you can’t simply say
» “we” in this context. I, for example, do not need
» any discussion-forum-members like e.g. “BaldHalfTruth” or forum members
» like “mj2003” …
» http://www.hairsite.com/hair-loss/board_entry-id-64827-page-0-category-1-order-last_answer-descasc-DESC.html
»
» … if I wish to know anything about specific things called “facts”: There
» exists e.g. other forums, blogs, chats etc. AND - you won’t believe that -
» real persons and telephones for simple communication too - IF I’m
» not sure about specific things/facts. So PLEASE, especially guys like you,
» shouldn’t use “we” (trying to implicating “there are lots of others behind
» me too” ) in a specific context, who are always just wait for informations
» by others.

Listen you chinese Nazi. Why r u always clowning on people when you’re the dumbest person on the forum? He has every right to say WE, but of course it excludes YOU. get a LIFE, a JOB perhaps, a friend or TWO, and face reality…you’re stupid.

123

» Listen you chinese Nazi. Why r u always clowning on people when you’re the
» dumbest person on the forum? He has every right to say WE, but of course it
» excludes YOU. get a LIFE, a JOB perhaps, a friend or TWO, and face
» reality…you’re stupid.

He’s f-cked up multiple threads, turning this sub-forum into a pigsty. Any useful information is buried by his bizarre flamewar rants.

124

» » Listen you chinese Nazi. Why r u always clowning on people when you’re
» the
» » dumbest person on the forum? He has every right to say WE, but of course
» it
» » excludes YOU. get a LIFE, a JOB perhaps, a friend or TWO, and face
» » reality…you’re stupid.
»
» He’s f-cked up multiple threads, turning this sub-forum into a pigsty.
» Any useful information is buried by his bizarre flamewar rants.

Hopefully Soon! He insults members who have actually have something intelligent to say and he seems to be incoherent. The most important thing this site does is keeps us informed, all Iron Man does is interfere with that.

125

» » Listen you chinese Nazi. Why r u always clowning on people when you’re
» the
» » dumbest person on the forum? He has every right to say WE, but of course
» it
» » excludes YOU. get a LIFE, a JOB perhaps, a friend or TWO, and face
» » reality…you’re stupid.
»
» He’s f-cked up multiple threads, turning this sub-forum into a pigsty.
» Any useful information is buried by his bizarre flamewar rants.

Yeah, please ban the clown. I’m surprised it hasn’t happened yet.

126

» » » » I agree, all of these trials look very promising and optimistic. I
» » think
» » » » that within 3 to 5 years this should hit the market. Very
» » » promising!
» » »
» » » Let’s say within the next 3 years. Maybe they’re not even forced by
» FDA
» » to
» » » do a phase III trail. YES, that COULD be possible too …
» »
» » yea… or maybe jesus’ second coming in june
» will bring hair to us all…
» » that COULD BE too…
» »
» » also what exactly do you find so promising we
» hardly know anything about
» » these trails
»
» It always seems, YOU hardly know anything. So you can’t simply say
» “we” in this context. I, for example, do not need
» any discussion-forum-members like e.g. “BaldHalfTruth” or forum members
» like “mj2003” …
» http://www.hairsite.com/hair-loss/board_entry-id-64827-page-0-category-1-order-last_answer-descasc-DESC.html
»
» … if I wish to know anything about specific things called “facts”: There
» exists e.g. other forums, blogs, chats etc. AND - you won’t believe that -
» real persons and telephones for simple communication too - IF I’m
» not sure about specific things/facts. So PLEASE, especially guys like you,
» shouldn’t use “we” (trying to implicating “there are lots of others behind
» me too” ) in a specific context, who are always just wait for informations
» by others.

hey iron_man,

i have to admit that i dont know of anyone on this board who finds your contributions so far useful. Can’t you please do us all a favor and refrain from posting unless you actually have something useful to say?

It would be greatly appreciated. Its in the interest of your creditability and the quality of this board

thanks.

127

Oh, YES, please HairSite-Admin ban me, because I’m „Mr. Nostradamus“ … :slight_smile:

Iron Man – January 20, 2010 (page 2, within this topic/thread):
» The colored text explains, WHY they did not always inject in completely
» bald areas. That means, in this case (test person), they test/check
» both:
»
» 1) in labs tissue engineered scaffolds (hair follicle shaped/created);
» 2) plus just (stem-)cells, to try to reactivate already natural existing
» “scaffolds” (follicle bulbs);

  1. = “follicle neogenesis” (new hairs from scratch)
  2. = “follicular rejuvenation” (autologous hair regeneration therapy)
    :confused:

Aderans - February 28, 2010:
„The second phase of the trial is testing a variety of treatment regimens designed to realize a unique autologous cell engineering solution to hair regeneration.”
Source: http://www.prweb.com/releases/hair/regeneration/prweb3661844.htm

“Variety” in this context means, which “regimens” = ”medicine” works best in which case/test-patient. In fact, they just test some other regimens/varieties too.

BTW #1: Most AGA-patients need step 2) BEFORE step 1)!! Please, guess just one time why … Among some other reasons, step 2) has been the most important reason, why Aderans couldn’t go to market some years ago (step 1 before step 2 makes not really sense).

BTW #2: For now I just can tell YOU, that - latest in about 1 year -,
I’ll be able to tell YOU “I hate to say ‘I told YOU so’ …”

BTW #3: Of course, I’m NOT “Nostradamus”. I’m just “Mr. Hair-Transplant-Killer” (means, somebody is trying to rescue imminent HT-victims as much as he can) … :lookaround:

128

you are not nostradamus nor are you mr. hair-transplant-killer… you are just a stupid idiot… seriously… i usually i try not to insult people on this board but i have to agree with mj2003 that you really are the dumbest guy in the forum… :frowning:

» Oh, YES, please HairSite-Admin ban me, because I’m „Mr. Nostradamus“ … :slight_smile:
»
»
» --------------------------------
» Iron Man – January 20, 2010 (page 2, within this topic/thread):
» » The colored text explains, WHY they did not always inject in completely
» » bald areas. That means, in this case (test person), they test/check
» » both:
» »
» » 1) in labs tissue engineered scaffolds (hair follicle shaped/created);
» » 2) plus just (stem-)cells, to try to reactivate already natural existing
»
» » “scaffolds” (follicle bulbs);
» --------------------------------
»
» 1) = “follicle neogenesis” (new hairs from scratch)
» 2) = “follicular rejuvenation” (autologous hair regeneration therapy)
» :confused:
» --------------------------------
» Aderans - February 28, 2010:
» „The second phase of the trial is testing a variety of
» treatment regimens designed to realize a unique autologous cell
» engineering solution to hair regeneration.”
» Source: http://www.prweb.com/releases/hair/regeneration/prweb3661844.htm
» --------------------------------
»
» “Variety” in this context means, which “regimens” = ”medicine” works best
» in which case/test-patient. In fact, they just test some other
» regimens/varieties too.
»
» BTW #1: Most AGA-patients need step 2) BEFORE step 1)!! Please, guess just
» one time why … Among some other reasons, step 2) has been the most
» important reason, why Aderans couldn’t go to market some years ago (step 1
» before step 2 makes not really sense).
»
» BTW #2: For now I just can tell YOU, that - latest in about 1 year -,
» I’ll be able to tell YOU “I hate to say ‘I told YOU so’ …”
»
» BTW #3: Of course, I’m NOT “Nostradamus”. I’m just “Mr.
» Hair-Transplant-Killer” (means, somebody is trying to rescue imminent
» HT-victims as much as he can) … :lookaround:

129

And when the HM-forum looked like it couldn’t get worse…
then Iron_Man appeared!! :lol2:

» » Listen you chinese Nazi. Why r u always clowning on people when you’re
» the
» » dumbest person on the forum? He has every right to say WE, but of course
» it
» » excludes YOU. get a LIFE, a JOB perhaps, a friend or TWO, and face
» » reality…you’re stupid.
»
» He’s f-cked up multiple threads, turning this sub-forum into a pigsty.
» Any useful information is buried by his bizarre flamewar rants.

130

When are we going to hear the results from ARI about their P2 trail? Can anyone reasonably guesstimate? It seems like it should be soon. Sorry if this has already been covered, recently I’ve gotten lost in this scattered forum.

ARI truly does have our lives in their hands. If they don’t succeed then it looks like were f*cked. No one else look as though they’re going to make this happen in our life time.

131

» When are we going to hear the results from ARI about their P2 trail? Can
» anyone reasonably guesstimate? It seems like it should be soon. Sorry if
» this has already been covered, recently I’ve gotten lost in this scattered
» forum.
»
» ARI truly does have our lives in their hands. If they don’t succeed then
» it looks like were f*cked. No one else look as though they’re going to
» make this happen in our life time.

Later this year seems to be the timeline. If we don’t hear anything by then, it’s probably down the drain. Either way, it’s still a good 5-6 years away from the market, even if the trials are successful. That’s an entire lifetime in itself.

132

» » When are we going to hear the results from ARI about their P2 trail?
» Can
» » anyone reasonably guesstimate? It seems like it should be soon. Sorry
» if
» » this has already been covered, recently I’ve gotten lost in this
» scattered
» » forum.
» »
» » ARI truly does have our lives in their hands. If they don’t succeed
» then
» » it looks like were f*cked. No one else look as though they’re going to
» » make this happen in our life time.
»
» Later this year seems to be the timeline. If we don’t hear anything by
» then, it’s probably down the drain. Either way, it’s still a good 5-6 years
» away from the market, even if the trials are successful. That’s an entire
» lifetime in itself.

True to that Buckerine11. Sadly, by that time it might not make that big of a difference (but I’de gladly still want it). Thanks for the reply! This info does seem to make sense to me.

133

I don’t know how, but I missed last BHT reply.
and it is quite important.

BHT, thanks for telling us the details of your new hairs, and sorry for the lack of reply on my side.

Well, we still don’t know if your new hairs are “brand new” or just “rejuvenated”. As you tell us the area is thinning, they could be rejuvenated. Although, at the same time, if they were generated by an scaffold, then they should be “brand new”.

If they are really brand new, then the fact that they look normal, in colour, callibre, and direction, is reaaaally a GREAT achievement! And it is the first step towards a baldness cure.
Why do I say it is just a “first step”?
well, because we don’t know if they can cycle or not.

So:
-If the new hairs are really brand new (neogenesis).
-And they can cycle

Then the cure is here!

And the fact that they are treating so many trialists will help to improve the efficiency (lower costs).

I am more optimist now, even if Aderans’ stocks remain dull.

BHT, what happened to the vellus hairs? did they get terminal?

Again, thank you.

p.d. what is the meaning of those bars and numbers under your post?

» Yes Spanish Dude.
» I looked closely at the new hairs again.
» They look completely normal to me… color and direction… as the
» scaffold intended. I’m glad it works for thinning areas. No shock fallout
» like HT.
» The tiny colorless vellus hairs seem darker now too… but sooooo thin and
» short.
» l l l l l l
» l l l l l l
» l l l l l l
» 1 11 11 111 1

134

» So:
» -If the new hairs are really brand new (neogenesis).
» -And they can cycle
»
» Then the cure is here!
»
» And the fact that they are treating so many trialists will help to improve
» the efficiency (lower costs).

You’re crazy! Can’t you read?

» buckerine11: “Either way, it’s still a good 5-6 years
» away from the market, even if the trials are successful. That’s an entire
» lifetime in itself.”

Guys like buckerine11, fckhrls, hairman2, mj2003 etc etc LIKE IT to tell others the truth. Because without the truth …
http://www.einzinger.de/catalog/images/products/08515-1.jpg

… they’ll NOT have someone anymore who listen to the truth … :frowning:

So shame on you, Spanish Dude, for destroying their nightmares!!!

135

» » They say when ARI phase II is going to be completed?
»
» one article said end2009, but who knows…

ari phase II has completed its study in the first city. now phase II is being conducted in several other cities.

phase I was done on mice. mice only have a life of two years. so how long the new hair will remain on humans should certainly be considered in phase III.

so for practical reasons, the first group of human participants have had the injections for only a year. what good would that new hair be if it had a short life span?

how many human participants do you feel are necessary for a research project like this? how long should that hair be in their scalp to be considered stable? is price or guarantee more important? what are the minimum expectations for you to consider this treatment. the only thing we can compare to, is regular hair transplants. this procedure has progressed from large plugs to mini plugs. this new procedure from ari is new. will it look natural, stay natural. that’s why trials are necessary to iron out any bugs before releasing it to the public.

these test participants walk around with tattoos on their scalps. how many of us, have jobs were you would be comfortable with visible tattoos on your scalp?

so let’s be helpful and provide ari with useful comments.

136

» » Sorry cal but its not as easy as that… 25% more hair is not the same as
» » 25% darker area of coverage in photoshop. Saying that would mean that a
» » person with 8 hairs on his head has 25% darker coverage with 10 hairs?
» Hair
» » count and coverage do not have a linear correlatation.
» »
» » Also the 25% improvement seems to be in areas of thinning hair, so on a
» » 5000 graft transplant i dont think the 25% applies to the transplanted
» hair
» » but rather to the thinning original hair, which might well be a far
» smaller
» » procentage.
» »
» »
» » » Take a pic of your thinning bald spot, get it into photoshop, and
» » darken
» » » the area by 25%. That’s a BIG improvement for anything working
» outside
» » the
» » » typical methods. That’s real.
» » »
» » » Or you could imagine it this way: Take a HT recipient area that has
» » had
» » » 4000 grafts implanted, and magically turn it into 5000 grafts. No
» » » additional hormone effects, and no loss of the regained hair as soon
» as
» » any
» » » daily medication regimens are stopped.
» » »
» » »
» » »
» » »
» » » If you guys can’t see the progress this represents then you’re not
» » being
» » » realistic about near-term HM. We haven’t ever seen jack sh*t in
» terms
» » of
» » » visible results from any other kind of HM project like this. And
» nobody
» » is
» » » saying this result is the final product of ARI’s project, either.
» » »
» » » I am pleased by the sound of this.
» Good point, but having 25% more hair in a thinning region, that can be
» used for a HT would be critical for many people.
»
» Bottom line is that if 25% increase in thinning areas is offered by ARI,
» assuming that it’s not going to be outrageous in price, would be more than
» useful for balding men.

what makes ‘hm’ unique is that people who have very limited amounts of hair can conceivably regrow a full head of hair. more hair cells can be produced in the lab to create as many injections necessary to get that full head of hair. unfornuately for many of us who have limited incomes, only those who can afford will be able to get it. until ari has competition from other ‘hm’ companies if this treatment is successful, it’s their monopoly to cash in.

137

» so for practical reasons, the first group of human participants have had
» the injections for only a year. what good would that new hair be if it had
» a short life span?
»
»
» how long should that hair be in their scalp to be
» considered stable? is price or guarantee more important? what are the
» minimum expectations for you to consider this treatment. the only thing we
» can compare to, is regular hair transplants.

Here you’ll find some answers in regard “stable”:
http://medicalnewstoday.healthology.com/hybrid/hybrid-autodetect.aspx?content_id=2187&focus_handle=hair-loss&brand_name=medicalnewstoday

BTW - Video/Interview (click “Read Transcript” ) has been produced in 2000 - not in 2008. In fact, the video is exactly 10 years old.

138

» » » They say when ARI phase II is going to be completed?
» »
» » one article said end2009, but who knows…
»
» ari phase II has completed its study in the first city. now phase II is
» being conducted in several other cities.
»
» phase I was done on mice. mice only have a life of two years. so how long
» the new hair will remain on humans should certainly be considered in phase
» III.
»
» so for practical reasons, the first group of human participants have had
» the injections for only a year. what good would that new hair be if it had
» a short life span?
»
» how many human participants do you feel are necessary for a research
» project like this? how long should that hair be in their scalp to be
» considered stable? is price or guarantee more important? what are the
» minimum expectations for you to consider this treatment. the only thing we
» can compare to, is regular hair transplants. this procedure has progressed
» from large plugs to mini plugs. this new procedure from ari is new. will it
» look natural, stay natural. that’s why trials are necessary to iron out any
» bugs before releasing it to the public.
»
» these test participants walk around with tattoos on their scalps. how many
» of us, have jobs were you would be comfortable with visible tattoos on your
» scalp?
»
» so let’s be helpful and provide ari with useful comments.

These are HUMAN clinical trials. They are not performed on mice. Experiments on mice are done in pre-clinical trials.

139

» » So:
» » -If the new hairs are really brand new (neogenesis).
» » -And they can cycle
» »
» » Then the cure is here!
» »
» » And the fact that they are treating so many trialists will help to
» improve
» » the efficiency (lower costs).
»
» You’re crazy! Can’t you read?
»
» » buckerine11: “Either way, it’s still a good 5-6
» years
» » away from the market, even if the trials are
» successful. That’s an entire
» » lifetime in itself.”
»
» Guys like buckerine11, fckhrls, hairman2, mj2003 etc etc LIKE IT to tell
» others the truth. Because without the truth …
» http://www.einzinger.de/catalog/images/products/08515-1.jpg
»
» … they’ll NOT have someone anymore who listen to the truth … :frowning:
»
» So shame on you, Spanish Dude, for destroying their nightmares!!!

geezes… you are such a useless contribution to this forum… your post didnt even make sense…

140

» » » They say when ARI phase II is going to be completed?
» »
» » one article said end2009, but who knows…
»
» ari phase II has completed its study in the first city. now phase II is
» being conducted in several other cities.
»
» phase I was done on mice. mice only have a life of two years. so how long
» the new hair will remain on humans should certainly be considered in phase
» III.
»
» so for practical reasons, the first group of human participants have had
» the injections for only a year. what good would that new hair be if it had
» a short life span?
»
» how many human participants do you feel are necessary for a research
» project like this? how long should that hair be in their scalp to be
» considered stable? is price or guarantee more important? what are the
» minimum expectations for you to consider this treatment. the only thing we
» can compare to, is regular hair transplants. this procedure has progressed
» from large plugs to mini plugs. this new procedure from ari is new. will it
» look natural, stay natural. that’s why trials are necessary to iron out any
» bugs before releasing it to the public.
»
» these test participants walk around with tattoos on their scalps. how many
» of us, have jobs were you would be comfortable with visible tattoos on your
» scalp?
»
» so let’s be helpful and provide ari with useful comments.

i really dont think our comments matter to ari at all… there is not much use for them in our discussions… people on this board tend to overestimate their importantce… this board merely satisfies our desire to discuss, speculate and most of all support and give each other hope that a treatment is near.

Hairloss is a bitch. Peace out.