@Bald-HalfTruth - adreans trial?

Stem cell; cell based hair therapy
41

»
» What is this? some sort of a human experiment? If I am not wrong you are
» using humans right?
» Is this legal? I’m just wondering. :slight_smile:

It’s hair multiplication/cloning and it isn’t available yet and no one knows when it will be available. Some of them claiming that the cure is round the corner but i know that they are doing those experiments several years already and it isn’t still available. At least there is a little hope.

Here you can read a little bit more about this http://www.aderansresearch.com
And here you can see some more info and timeline http://tressless.com/learn/Hair_Multiplication

42

Caroline, its ARI (Aderans Research Institute).
They are now conducting phase II trials, on men and women.

» » » » » LOL.
» » » » » And how do we know it is him and not a troll playing silly games?
» » » » » I am afraid we will have to wait until ARI tells us something.
» » » » » In theory, PhaseII trials should be already completed (the plan
» was
» » » to
» » » » » finish them by year’s end).
» » » » » If they go on to phaseIII that will mean that PhaseII was
» » successful.
» » » » » Remember that the test subjects were very bald, not the
» thinning
» » » crap
» » » » we
» » » » » are used to see in past trials. These are genuinelly bald men
» and
» » » » women
» » » » » so they are surely trying neogenesis.
» » » » »
» » » »
» » » » We will have to wait longer. The trial lasts for 12 months
» therefore
» » we
» » » » wont get any results until mid to late 2010.
» » » »
» » » » I read an article claiming the trial would finish towards the end
» of
» » » 2009
» » » » aswell but clearly that was an error.
» » »
» » » I don’t remember where did I read it, but I didn’t have the
» impression
» » » that it was an error. More probably an optimistic projection. Also,
» it
» » » depends on what do we mean by “end of the trial”. Of course, if you
» » wait
» » » for all the data to be compiled, processed, etc, it will take much
» » more.
» » » Damn, BHT, where are you!!
» »
» » Here is the sentence :
» »
» » He hopes to have better luck in clinical trials, when he will
» transplant
» » human cells into
» » humans. Aderans is in the second phase of a human trial, which is
» expected
» » to be completed by the end of the
» » year.
» »
» » This is from : http://www.aderansresearch.com/ari_ournews.html
» »
» » In the Document : March 2009 : The new science of hair growth
» »
» » Cheers
»
»
» » Here is the sentence :
» »
» » He hopes to have better luck in clinical trials, when he will
» transplant
» » human cells into
» » humans. Aderans is in the second phase of a human trial, which is
» expected
» » to be completed by the end of the
» » year.
» »
»
»
» What is this? some sort of a human experiment? If I am not wrong you are
» using humans right?
» Is this legal? I’m just wondering. :slight_smile:

43

Can’t reveal much.
(Got in trouble.)
Hair growth is good… not great. (Jan. 18, 2010)
I’d estimate about a 20% increase in density in the test area.
(Meaning about one new follicle for every 4 existing follicles.)
They say that should increase with time. Let’s see.

44

Yessss!!! :stuck_out_tongue:

45

» Can’t reveal much.
» (Got in trouble.)
» Hair growth is good… not great. (Jan. 18, 2010)
» I’d estimate about a 20% increase in density in the test area.
» (Meaning about one new follicle for every 4 existing follicles.)
» They say that should increase with time. Let’s see.
Shouldn’t that be 25% in density? You went from 4 to 5 follicles.

Either way, that’s amazing! Is that with one treatment only? Would more treatments mean more than 25% growth?

46

» Can’t reveal much.
» (Got in trouble.)
» Hair growth is good… not great. (Jan. 18, 2010)
» I’d estimate about a 20% increase in density in the test area.
» (Meaning about one new follicle for every 4 existing follicles.)
» They say that should increase with time. Let’s see.

Somone knows which were Intercytex phase 2 results? They gave something out but i don’t know how to compare those results with this guy. Didn’t they got the same results like this guy and their phase 2 failed and now company is broke too? now i little bit worry about ari’s success :expressionless:

link to intercytex results:
http://www.intercytex.com/icx/products/aesthetic/icxtrc/

47

Assuming the new hair growth is normal (color, characteristics, cycling, direction, etc) this sounds like good news to me.

1 new hair in 4-5 is good enough to call it progress. That’s probably enough to wanna put the stuff on the market in some form. It’s too much to be a coincidence, and it means the technology would be a cosmetically visible gain even if it never gets any better.

48

» Assuming the new hair growth is normal (color, characteristics, cycling,
» direction, etc) this sounds like good news to me.
»
» 1 new hair in 4-5 is good enough to call it progress. That’s probably
» enough to wanna put the stuff on the market in some form. It’s too much to
» be a coincidence, and it means the technology would be a cosmetically
» visible gain even if it never gets any better.

Is ARI an injection like Histogen? If so, I wonder if the 20% increase in density is dependent on the original density, or if the 20% that BaldHalfTruth saw was just coincidentally 20% of his original density.

49

ARI is more comparable to ICX’s failed effort than Histogen IMHO. ARI is doing the job in a more complex series of steps than ICX ever did, but the basic idea of multiplying & reimplanting dermal papillae cells is similar. It’s less about fabricating new hairs, and more about transferring the DHT resistance of the donor area to the injection sites.

50

»
» Is ARI an injection like Histogen? If so, I wonder if the 20% increase in
» density is dependent on the original density, or if the 20% that
» BaldHalfTruth saw was just coincidentally 20% of his original density.

ARI tests HM. they remove some DHT resist hair from your donor area back of the head, culturing them in lab and then injecting cells back to bald area. those cells shoud develop new hair and the result should be full head of hair (best case). i understood that those injected cells should rejuvenate old dead hair too.

Bald-HalfTruth - did you got treatment to completely bald area or you had your own old hair on that area too?

51

» Can’t reveal much.
» (Got in trouble.)
» Hair growth is good… not great. (Jan. 18, 2010)
» I’d estimate about a 20% increase in density in the test area.
» (Meaning about one new follicle for every 4 existing follicles.)
» They say that should increase with time. Let’s see.

20% is reasonable.

If those results are compoundable (to a certain extent), and if the pricepoint’s set at a reasonable rate for the average joe than - and only than - I think we can conclude Aderans has a real game changer on their hands. A product that caps out at 20% wouldn’t be that bad either. It wouldn’t be the silver bullet everyone wanted, but I’m sure it would still help allot of people… particularly those in the early stages of hairloss, with stabilized/minimal hairloss, or those contemplating an ht.

Thanks for the update Bald-HalfTruth.

52

» Can’t reveal much.
» (Got in trouble.)
» Hair growth is good… not great. (Jan. 18, 2010)
» I’d estimate about a 20% increase in density in the test area.
» (Meaning about one new follicle for every 4 existing follicles.)
» They say that should increase with time. Let’s see.

You don’t know if you got a placebo or not, right?

53

»
» You don’t know if you got a placebo or not, right?

If we could get 20% regrowth with each round of placebo wounding, then we wouldn’t need any new HM technology in the first place.

54

» »
» » You don’t know if you got a placebo or not, right?
»
»
» If we could get 20% regrowth with each round of placebo wounding, then we
» wouldn’t need any new HM technology in the first place.

Hey, be careful, don’t talk too much about the placebo effect, or we could have Dr. Hitzig offering hair cloning using placebo injections very soon.

55

Hi Bald-HalfTruth, thanks your your much-awaited reply.
I am sorry you got in trouble. Was it because you posted here?
There is something I don’t understand: you said that your couldn’t post here freely because your identity was revealed. How was that?

As you talk about 1 new har for each 4 preexistant hairs, I assume the test area is not completely bald, but just thinning, is that correct?
But you said there were 4 test areas…in which area are you having regrowth?
If it is thinning, and not bald, this is bad news, because I expected a totally bald area. ICX and Histogen also tested on thinning areas. Regrowing hair on thinning areas is easier, because you have weakened follicles that you can revive. 20% or 25% is achievable with Minoxidil, or Propecia, or Histogen.
so, maybe, these follicles are not new, but just rejuvenated. This is surprising to me, because I expected ARI to use scaffolds, and this means, I think, neogenesis.
Still, note that we don’t know the number of “injections” or scaffolds. Maybe you got 1 hair for each 4 preexisting hairs, because you only got 1 injection/scaffold for each 4 preexisting hairs. The important figure is number of hairs per injection/scaffolds. (should be 1/1)

The good news is that you are a real trialist. The good news is that you are not the best, handpicked result. If we consider this, 20% or 25% increase could be considered a good starting point.
We will see if you still can increase the number of hairs. When were you injected?

In the previous update you said that you were seeing new, colourless hairs, but you had seen the same result with Propecia (I assume you quit Propecia afterwards) and these “propecia hairs” never
got colour. Are now the “ARI-hairs” getting colour?.

again, thanks for the update, and sorry for so many questions :slight_smile:

» Can’t reveal much.
» (Got in trouble.)
» Hair growth is good… not great. (Jan. 18, 2010)
» I’d estimate about a 20% increase in density in the test area.
» (Meaning about one new follicle for every 4 existing follicles.)
» They say that should increase with time. Let’s see.

56

» 20% is reasonable.

No. For the end product - no.

It would be smart not focus on such or any such clinical trail results, because they are currently just test/check important other things (e.g. bio-absorbable properties and so on in some different ways) - nothing more.

57

» Can’t reveal much.
» (Got in trouble.)
» Hair growth is good… not great. (Jan. 18, 2010)
» I’d estimate about a 20% increase in density in the test area.
» (Meaning about one new follicle for every 4 existing follicles.)
» They say that should increase with time. Let’s see.

Thanks again for the update. Dont get yourslf into trouble by revealing too much, but its great to hear any progress that is occurring. Do you meet any other patients undergoing the trial when you go for testing?

58

» » 20% is reasonable.
»
» No. For the end product - no.
»
» It would be smart not focus on such or any such clinical trail
» results, because they are currently just test/check important other things
» (e.g. bio-absorbable properties and so on in some different ways) - nothing
» more.

20% would be ok if: 1.That figure was repeated with additional injections 2. It was at a reasonable price.

But your right results are irrelevant at this stage in terms of working out the effectiveness of the end product. Not least because we dont even know how many injections have been administered. Lets say 100 injections were given and all of them gave great terminal hair. Cosmetically it would look crap, even though the results were perfect (ie. 100% of the injections successful). On the other hand, if you gave 100,000 injections and got 100 great terminal hair (ie.0.1% of the injections successful) the hair would look the same but the trial results would be terrible. (Edit: Sorry just realised Spanish Dude made the same point more succinctly!)

I am just glad we are seeing positive results at the moment ie. hair growth. Only once the trial is finished and all the data is available can we determine if the product is likley to be effective.

59

Spanish Dude.
I never had any TOTALLY bald areas… just thinning.
There are two test areas on my scalp.
Both are showing the same results.
The researchers don’t tell me the results. I’m just going by my own observations with a mirror and a magnifying glass.
One small area originally had 20 hairs. Now it has 25.
That’s actually a 25% increase.
I also notice these very small colorless hairs created (like peach fuzz) that I’m not counting yet. Hopefully they’ll develop too.
My name was revealed on ANOTHER website. So I won’t be talking about techniques at all… just results. And pix are strictly forbidden.

60

so this doesnt actually grow new hair as much as it blocks dht??? im just assuming this from what cal said but i may have interpreted what he said.