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Allergan aims to develop Latisse for baldness


#1

When new rumors surfaced of a potential Allergan buyout, we confess we skipped right over “anti-baldness drugs” in the long list of reasons why GlaxoSmithKline or Sanofi-Aventis might be interested in bidding. But during the company’s second-quarter earnings call, Allergan officials gave some hints about just what that remedy would be. And lo and behold, they’re talking about Brooke Shields’ favorite eyelash grower, Latisse.

Yep, the glaucoma drug turned cosmeceutical is now under testing as a baldness-fighter. And as Jim Edwards at BNet Pharma points out, if Latisse (a.k.a Lumigan for glaucoma and bimatoprost generically) proves effective against hair loss, then Katie bar the door. Allergan would have a megablockbuster on its hands.

But there’s good news for companies that might want to snap up Allergan before Latisse-for-baldness becomes a sure thing, while its stock price is still on the low side–and cheap, if the baldness use came to be. Allergan is “sort of starting from scratch” on testing the drug for baldness, EVP Scott Whitcup said during the Q2 investor call. In fact, Allergan is scrambling in the early stages. “We are working as quickly as we can to get a formulation, get the preclinical work done and into the clinic,” Whitcup said.


#2

Interesting find. I wonder if it will take less time for the FDA approval process since it is already approved for eyelash growth. Hair and eyelash, not that much different, don’t you think?


#3

» http://www.fiercepharma.com/story/allergan-aims-develop-latisse-baldness/2009-08-12
»
»
» When new rumors surfaced of a potential Allergan buyout, we confess we
» skipped right over “anti-baldness drugs” in the long list of reasons why
» GlaxoSmithKline or Sanofi-Aventis might be interested in bidding. But
» during the company’s second-quarter earnings call, Allergan officials gave
» some hints about just what that remedy would be. And lo and behold, they’re
» talking about Brooke Shields’ favorite eyelash grower, Latisse.
»
» Yep, the glaucoma drug turned cosmeceutical is now under testing as a
» baldness-fighter. And as Jim Edwards at BNet Pharma points out, if Latisse
» (a.k.a Lumigan for glaucoma and bimatoprost generically) proves effective
» against hair loss, then Katie bar the door. Allergan would have a
» megablockbuster on its hands.
»
» But there’s good news for companies that might want to snap up Allergan
» before Latisse-for-baldness becomes a sure thing, while its stock price is
» still on the low side–and cheap, if the baldness use came to be. Allergan
» is “sort of starting from scratch” on testing the drug for baldness, EVP
» Scott Whitcup said during the Q2 investor call. In fact, Allergan is
» scrambling in the early stages. “We are working as quickly as we can to get
» a formulation, get the preclinical work done and into the clinic,” Whitcup
» said.

This only makes sense.
Add another to the race. Competition is good.
In 10-15 years, going bald (provided you have the funds) will absolutely be a choice.


#4

» This only makes sense.
» Add another to the race. Competition is good.
» In 10-15 years, going bald (provided you have the funds) will absolutely
» be a choice.

It will be interesting to see if any DIYers have success with it.


#5

Yeah, I see no reason to get wound up with hopes over this one yet.

Minox spurs growth too. But it hasn’t exactly put HM research on the back burner.


#6

As long as it is not too expensive, I wouldn’t mind giving another topical a try. Who knows maybe minoxidil and Latisse together will do the trick for me.


#7

From the Allergan earnings conference call…spurred on from an analysts question:

Now, for wonderful things, finally something for us men as well. Scott is leading the charge there.
<A – Scott Whitcup>: So, Gregg, we are in the midst of looking at a number of formulations for bimatoprost for hair growth on the scalp. Unlike LUMIGAN for glaucoma, we don‟t have the eight years plus of clinical trials data. So we‟re sort of starting from scratch. So it‟s a little too early to give you the final timeline, but we are working as quickly as we can to get a formulation, get the preclinical work done and into the clinic, and we‟ll update you as soon as we have more a firm timeline.
<A – David Pyott>: And we‟re also doing work on patients who unfortunately have undergone chemotherapy. So there‟s a compassionate part of this story as well.
<A – Scott Whitcup>: Right. To David‟s point, we have a couple of programs for eyelash growth. We have studies to get this approved around the world. And then, as part of our FDA advisory committee, there was strong support for us using this in children who‟ve lost their eyelashes post-chemotherapy. And those studies are soon to kick off as well.
<Q – Gregg Gilbert>: After the male product you might be able to get your hands on the trademark for “MATISSE” – just a suggestion


#8

I predict it s going to be a long wait for this one.

» From the Allergan earnings conference call…spurred on from an analysts
» question:
»
» Now, for wonderful things, finally something for us men as well. Scott is
» leading the charge there.
» <A – Scott Whitcup>: So, Gregg, we are in the midst of looking at a number
» of formulations for bimatoprost for hair growth on the scalp. Unlike
» LUMIGAN for glaucoma, we don‟t have the eight years plus of clinical
» trials data. So we‟re sort of starting from scratch. So it‟s a
» little too early to give you the final timeline, but we are working as
» quickly as we can to get a formulation, get the preclinical work done and
» into the clinic, and we‟ll update you as soon as we have more a firm
» timeline.
» <A – David Pyott>: And we‟re also doing work on patients who
» unfortunately have undergone chemotherapy. So there‟s a compassionate
» part of this story as well.
» <A – Scott Whitcup>: Right. To David‟s point, we have a couple of
» programs for eyelash growth. We have studies to get this approved around
» the world. And then, as part of our FDA advisory committee, there was
» strong support for us using this in children who‟ve lost their
» eyelashes post-chemotherapy. And those studies are soon to kick off as
» well.
» <Q – Gregg Gilbert>: After the male product you might be able to get your
» hands on the trademark for “MATISSE” – just a suggestion


#9

» I predict it s going to be a long wait for this one.
»
» » From the Allergan earnings conference call…spurred on from an
» analysts
» » question:
» »
» » Now, for wonderful things, finally something for us men as well. Scott
» is
» » leading the charge there.
» » <A – Scott Whitcup>: So, Gregg, we are in the midst of looking at a
» number
» » of formulations for bimatoprost for hair growth on the scalp. Unlike
» » LUMIGAN for glaucoma, we don‟t have the eight years plus of
» clinical
» » trials data. So we‟re sort of starting from scratch. So it‟s
» a
» » little too early to give you the final timeline, but we are working as
» » quickly as we can to get a formulation, get the preclinical work done
» and
» » into the clinic, and we‟ll update you as soon as we have more a
» firm
» » timeline.
» » <A – David Pyott>: And we‟re also doing work on patients who
» » unfortunately have undergone chemotherapy. So there‟s a
» compassionate
» » part of this story as well.
» » <A – Scott Whitcup>: Right. To David‟s point, we have a couple of
» » programs for eyelash growth. We have studies to get this approved
» around
» » the world. And then, as part of our FDA advisory committee, there was
» » strong support for us using this in children who‟ve lost their
» » eyelashes post-chemotherapy. And those studies are soon to kick off as
» » well.
» » <Q – Gregg Gilbert>: After the male product you might be able to get
» your
» » hands on the trademark for “MATISSE” – just a suggestion

Some one want to buy some Latisse and put in on their scalp? Couldn’t hurt.


#10

It does not work. I tried it for 2 months and it did nothing. Others have also tried so we should have known if it grew scalp hair by now.


#11

» It does not work. I tried it for 2 months and it did nothing. Others have
» also tried so we should have known if it grew scalp hair by now.

what doesn’t work? Did you put Latisse on your scalp or you are talking about eyelash ?


#12

» » It does not work. I tried it for 2 months and it did nothing. Others
» have
» » also tried so we should have known if it grew scalp hair by now.
»
» what doesn’t work? Did you put Latisse on your scalp or you are talking
» about eyelash ?
My scalp. It is proven to work on eyelashes, not questioning that.


#13

» It does not work. I tried it for 2 months and it did nothing. Others have
» also tried so we should have known if it grew scalp hair by now.

2 months is hardly long enough to evaluate efficacy. You’d have to do it for at least 6 months. Not that I advocate doing that.


#14

» » It does not work. I tried it for 2 months and it did nothing. Others
» have
» » also tried so we should have known if it grew scalp hair by now.
»
» 2 months is hardly long enough to evaluate efficacy. You’d have to do it
» for at least 6 months. Not that I advocate doing that.
Anything I have used that worked showed results in two months regardles of the full amount of treatment time. But if people need to believe in this new treatment dont listen to me. Wait a few years and then we will see.


#15

There may be some minor gain from this stuff but I would extremely surprised if it did much.

If the hair gains were significant then I just don’t think the story would have stayed quiet. You KNOW the company must have at least considered the possibility of scalp hair regrowth application. Years ago.

Not to mention the scattered people who have doubtlessly tried it on the scalp too. (As if there aren’t plenty of women who might wanna thicken their hair already.)


#16

» » » It does not work. I tried it for 2 months and it did nothing. Others
» » have
» » » also tried so we should have known if it grew scalp hair by now.
» »
» » 2 months is hardly long enough to evaluate efficacy. You’d have to do
» it
» » for at least 6 months. Not that I advocate doing that.
» Anything I have used that worked showed results in two months regardles of
» the full amount of treatment time. But if people need to believe in this
» new treatment dont listen to me. Wait a few years and then we will see.

I don’t “need to believe in this new treatment”, I’m simply stating common guidelines for most hairloss protocols. Hair grows slowly, and most treatments take several months to show efficacy (proscar, Dut, Minox, all take at least 4 months to show any gains, and often longer). At the end of two months, even if it began to do something the day you started treatment, you’d have very minimal if not invisible (to the naked eye) growth.


#17

» I don’t “need to believe in this new treatment”, I’m simply stating common
» guidelines for most hairloss protocols. Hair grows slowly, and most
» treatments take several months to show efficacy (proscar, Dut, Minox, all
» take at least 4 months to show any gains, and often longer). At the end of
» two months, even if it began to do something the day you started treatment,
» you’d have very minimal if not invisible (to the naked eye) growth.

You’re quite right, only two months is really a waste of money and time because, in that case, you had better not to start it, for example someone posted these pics in a forum, it’s not in english but it doesn’t matter, the only important thing is that each pic is one month later than the previous one, you can see the evolution month by month, he was using minoxidil + ketoconazole :

http://foro.recuperarelpelo.com/viewtopic.php?t=7213&postdays=0&postorder=asc&start=0

That’s the problem with topicals, it’s really a pain in the *ss to follow the treatment with consistency, but it’s the only way.

About this “new” treatment, it has been said previously that the concentration for scalp hair regrowth should be higher, not to mention it’s expensive if you are going to apply it over your head, and maybe it won’t work, but it is interesting.


#18

» » I don’t “need to believe in this new treatment”, I’m simply stating
» common
» » guidelines for most hairloss protocols. Hair grows slowly, and most
» » treatments take several months to show efficacy (proscar, Dut, Minox,
» all
» » take at least 4 months to show any gains, and often longer). At the end
» of
» » two months, even if it began to do something the day you started
» treatment,
» » you’d have very minimal if not invisible (to the naked eye) growth.
»
» You’re quite right, only two months is really a waste of money and time
» because, in that case, you had better not to start it, for example someone
» posted these pics in a forum, it’s not in english but it doesn’t matter,
» the only important thing is that each pic is one month later than the
» previous one, you can see the evolution month by month, he was using
» minoxidil + ketoconazole :
»
» http://foro.recuperarelpelo.com/viewtopic.php?t=7213&postdays=0&postorder=asc&start=0
»
» That’s the problem with topicals, it’s really a pain in the *ss to follow
» the treatment with consistency, but it’s the only way.
»
» About this “new” treatment, it has been said previously that the
» concentration for scalp hair regrowth should be higher, not to mention it’s
» expensive if you are going to apply it over your head, and maybe it won’t
» work, but it is interesting.

Those are impressive pics. His hair cut gets longer, but you can still see some real regrowth starting at around month 5.

As for slathering on an eyelash drug on your head, you’re absolutely right, dosage is obviously key. Its going to be a while before they figure out a formula that works (if it works at all). If I were a DIYer (and I’m not - not worth the risk), I’d stay on it for at least 6-8 months before I drew any conclusions (which would only be preliminary, as the effective dosage is unknown).


#19

Greetings. First post though been following info on this site for a couple of years.
Anyways, found this video on a different hair loss site and decided to post it here. It looks like a doctor in Florida has been testing bimatoprost, the key ingredient in Latisse. Definitely at a preliminary stage at this point but hopefully this will show some potential.


#20

(bumping roger_that’s threads off the bottom of the page)