» » » I don’t know why you are suddenly so fond of Dr. Sinclair, while you
» are
» » » very negative in general. Is he a relative of yours? Family? Or is
» just
» » » part of your trolling activity in the forum?
» » »
» »
» » Dr. Sinclair is my father (and my clone – it’s very complicated). I
» also
» » own 99% of the stock in his company.
» »
» » Other than that, I have ABSOLUTELY NO CONNECTION to Dr. Sinclair!
»
» Then lets disconnect him. Right now, he has absolutely nothing that
» deserves attention.
The ironic part is that some of the members here want something that is proven before they even want to discuss it. News Flash…then there is nothing to discuss.
» » » » I don’t know why you are suddenly so fond of Dr. Sinclair, while you
» » are
» » » » very negative in general. Is he a relative of yours? Family? Or is
» » just
» » » » part of your trolling activity in the forum?
» » » »
» » »
» » » Dr. Sinclair is my father (and my clone – it’s very complicated). I
» » also
» » » own 99% of the stock in his company.
» » »
» » » Other than that, I have ABSOLUTELY NO CONNECTION to Dr. Sinclair!
»
» »
» » Then lets disconnect him. Right now, he has absolutely nothing that
» » deserves attention.
»
» The ironic part is that some of the members here want something that is
» proven before they even want to discuss it. News Flash…then there
» is nothing to discuss.
It is pointless to discuss Dr. Sinclair’s research. He is doing nothing new, its just the classical DP cells culturing, in very early stages. I don’t know why is he doing this. This has been tried by so many researchers before, and no results. ARI is using several cells, not just one. Trichoscience (Mc Elwee and others) are using a different kind of cell… This could be worth discussing, but not Sinclair’s DP experiments.
» no, DP cells are totally different than stem cells.
» DP cells are at the bottom of the hair bulb, while stem cells are mainly
» at the bulge (close to the surface).
» Stem cells are undifferenciated, pluripotential, and they reside mainly at
» the bulge.
» Stem cells can turn into different kinds of differentiated cells, for
» example DP cells. Stem cells travel from the bulge, downwards, to the bulb
» of the follicle, and then turn into DP cells or other types.
»
COMPARISON:
Conclusion - Reviewed October/November 2009 Dermal cells play a pivotal role in the regulation of hair growth. For hair follicle regeneration purposes, important issues include isolation of inductive dermal population, expanding their number by culture, maintenance of their hair inductive property and providing them an adequate niche and exogenous signals to enhance their interaction with epidermal cells toward the fate of hair neogenesis. An ideal hair regeneration model for human hair follicles has yet to be developed. The efficiency has to be improved with fewer starting cell number and higher number of regenerated hair follicles. The variables should be easily controllable for studying hair biology. The multipotent cells reside in dermal compartment [called “the bulge”?] of the hair follicle warrant further studies for their potential clinical application in regenerative medicine.
By Dr. George Cotsarelis and Dr. Chao-Chun Yang
So who is wrong and who is right? Spanish Dude or Dr. Cotsarelis?
An what could be “an ideal hair regeneration model”?
Why Dr. Cotsarelis (Follica) lately hired additional staff?
You may be right because all this Acell-Histogen-Follica-PRP-personal experiment stuff is a bunch of crap and won't lead anywhere except into a blind alley.
The only other hope out there right now might be Dr. Sinclair in Melbourne, Australia, who is working with stem cell cultures.
Any idea which doesn’t involve actual CELLS is a waste of time in my opinion…
That includes ALL topicals, cell extracts, solutions, vitamins, enzymes, hormones, minerals, drugs, pills, etc.
Does anyone else remember where the best examples of actual, usable, cosmetically significant regrowth on humans have come from so far?
Not Aderans.
Not ICX-TRC.
Not Histogen.
Not Dr Sinclair, not Dr. Gho, and not Dr. Armani.
It’s been the accidental examples of Folica-like scenarios.
I don’t like the signs of Folica’s inactivity these days either, but IMHO we’ve still got at least as much viable reason to believe in that plan as any of the other HM operations.
» Does anyone else remember where the best examples of actual, usable,
» cosmetically significant regrowth on humans have come from so far?
»
»
» Not Aderans.
» Not ICX-TRC.
» Not Histogen.
» Not Dr Sinclair, not Dr. Gho, and not Dr. Armani.
»
»
» It’s been the accidental examples of Folica-like scenarios.
Correct!
BUT keep in mind: E.g. Aderans or Intercytex ICX-TRC or TrichoScience they already had their “accidents” (they patented) in their labs FAR BEFORE e.g. Follica or Histogen or Dr. Sinclair had their “accidents” in their labs.
And exactly there you can find the reason,
WHY e.g. Histogen currently have problems with patent infringement - and some others (pretty sure Follica too within the next years) will be the next ones with problems in this regard …
Are you guys completely blind about what’s going on out there??
Sorry Iron_Man, but, once again, I am not sure if I understand your point. You speak a weird language. I am not saying that your english is bad, but the way you express your ideas is weird. Maybe you speak weird to appear more interesting? Please, speak in simpler terms. Maybe I am too simple
I did my homework years ago. And I tell you, DERMAL PAPILLA CELLS are not STEM CELLS. Where does Cotsarellis contradict me? In that text, he is not saying that Dermal papilla cells are multipotent.
It is true that the Dermal Papilla regulates hair growth and cycling, but they are not stem cells.
» » no, DP cells are totally different than stem cells.
» » DP cells are at the bottom of the hair bulb, while stem cells are
» mainly
» » at the bulge (close to the surface).
» » Stem cells are undifferenciated, pluripotential, and they reside mainly
» at
» » the bulge.
» » Stem cells can turn into different kinds of differentiated cells, for
» » example DP cells. Stem cells travel from the bulge, downwards, to the
» bulb
» » of the follicle, and then turn into DP cells or other types.
» »
» -----------
» COMPARISON:
» -----------
» 8. Conclusion - Reviewed October/November 2009
» Dermal cells play a pivotal role in the regulation of hair growth.
» For hair follicle regeneration purposes, important issues include isolation
» of inductive dermal population, expanding their number by culture,
» maintenance of their hair inductive property and providing them an adequate
» niche and exogenous signals to enhance their interaction with epidermal
» cells toward the fate of hair neogenesis.
» An ideal hair regeneration model for human hair follicles has yet
» to be developed. The efficiency has to be improved with fewer starting cell
» number and higher number of regenerated hair follicles. The variables
» should be easily controllable for studying hair biology. The
» multipotent cells reside in dermal compartment [called
» “the bulge”?] of the hair follicle warrant further studies for their
» potential clinical application in regenerative
» medicine.
»
» By Dr. George Cotsarelis and Dr. Chao-Chun Yang
» -------------
»
» So who is wrong and who is right? Spanish Dude or Dr. Cotsarelis?
»
»
» An what could be “an ideal hair regeneration model”?
»
» Why Dr. Cotsarelis (Follica) lately hired additional staff?
»
» So do your homework …
» Sorry Iron_Man, but, once again, I am not sure if I understand your point.
» You speak a weird language. I am not saying that your english is bad, but
» the way you express your ideas is weird. Maybe you speak weird to appear
» more interesting? Please, speak in simpler terms. Maybe I am too simple
Oh, sorry Spanish Dude. I think I forgot to mention, that I’m from Austria (not “Australia” ). I’m just a member from a German hairloss board, so here we speak and write GERMAN all day long. That means, to write (and explain) in ENGLISH is sometimes not easy for me - but I try my best.
Regarding “weird language”:
You noticed that right. Sometimes I see no other way to speak clear, so I do it sometimes in German too. Reason: It makes not always sense “to speak clear” …
» And I tell you, DERMAL PAPILLA CELLS are not
» STEM CELLS. Where does Cotsarellis contradict me? In that text, he is not
» saying that Dermal papilla cells are multipotent.
»
» It is true that the Dermal Papilla regulates hair growth and cycling, but
» they are not stem cells.
Who said, that you’re wrong? The comparison (Spanish Dude vs. Dr. Cotsarelis) should just prove that you’re absolutely right, and other users can read (compare) that for themself.
» I did my homework years ago.
Same here.
So I think what we’re doing here is just to share our informations: I give you a hint, you give me a hint - but maybe I’m wrong ?
» » Sorry Iron_Man, but, once again, I am not sure if I understand your
» point.
» » You speak a weird language. I am not saying that your english is bad,
» but
» » the way you express your ideas is weird. Maybe you speak weird to
» appear
» » more interesting? Please, speak in simpler terms. Maybe I am too simple
»
»
» Oh, sorry Spanish Dude. I think I forgot to mention, that I’m from Austria
» (not “Australia” ). I’m just a member from a German hairloss board, so here
» we speak and write GERMAN all day long. That means, to write (and explain)
» in ENGLISH is sometimes not easy for me - but I try my best.
»
» Regarding “weird language”:
» You noticed that right. Sometimes I see no other way to speak clear, so I
» do it sometimes in German too. Reason: It makes not always sense “to speak
» clear” …
»
» » And I tell you, DERMAL PAPILLA CELLS are not
» » STEM CELLS. Where does Cotsarellis contradict me? In that text, he is
» not
» » saying that Dermal papilla cells are multipotent.
» »
» » It is true that the Dermal Papilla regulates hair growth and cycling,
» but
» » they are not stem cells.
»
» Who said, that you’re wrong? The comparison (Spanish Dude vs. Dr.
» Cotsarelis) should just prove that you’re absolutely right, and other users
» can read (compare) that for themself.
»
» » I did my homework years ago.
»
» Same here.
»
» So I think what we’re doing here is just to share our informations: I give
» you a hint, you give me a hint - but maybe I’m wrong ?
BTW - Dr. Sinclair is doing the same (speak NOT clear). I KNOW he know far MORE than you and I about the entire HM industry and HOW things work. So read between the lines in the article about Dr. Sinclair …
» BTW - Dr. Sinclair is doing the same (speak NOT clear). I KNOW he know far
» MORE than you and I about the entire HM industry and HOW things work. So
» read between the lines in the article about Dr. Sinclair …
Reading between Sinclair’s lines? there is nothing between his lines.
Besides, if I were to read between lines, every charlatan could be interpreted as correct.
Sinclair said what he said. And it is very clear. He has just done a few typical DP cultures, and thats all. Don’t try to see stem cell between the lines, lol.
p.d: I thought that you were German, as you misstyped some words in German. But the problem as I said is not the language, it is that you express yourself obscurely on purpose.
» » BTW - Dr. Sinclair is doing the same (speak NOT clear). I KNOW he know
» far
» » MORE than you and I about the entire HM industry and HOW things work.
» So
» » read between the lines in the article about Dr. Sinclair …
»
» Reading between Sinclair’s lines? there is nothing between his lines.
» Besides, if I were to read between lines, every charlatan could be
» interpreted as correct.
» Sinclair said what he said. And it is very clear.
Really? It is very clear?
That means, you believe in everything what you read, because something is clear formulated? Hm, why not …
» » » BTW - Dr. Sinclair is doing the same (speak NOT clear). I KNOW he know
» » far
» » » MORE than you and I about the entire HM industry and HOW things work.
» » So
» » » read between the lines in the article about Dr. Sinclair …
» »
» » Reading between Sinclair’s lines? there is nothing between his lines.
» » Besides, if I were to read between lines, every charlatan could be
» » interpreted as correct.
» » Sinclair said what he said. And it is very
» clear.
»
» Really? It is very clear?
»
» That means, you believe in everything what you read, because something is
» clear formulated? Hm, why not …
Why do you come here and speak in riddles? It’s very hard to understand what point you are trying to make most of the time.
» » Why do you come here and speak in riddles? It’s very hard to understand
» » what point you are trying to make most of the time.
»
» Why did you come here? YOU spoke always (at least mostly) CLEAR sentences.
» Right? But did you have success with your clear posts/messages?
»
» All I try to do is to clarify some things - at least, I try it. And yes,
» sometimes I use a ambiguous way.
»
» But let us talk about ACell, or Follica, or Dr. Sinclair or how bald are
» some heads can be …
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