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5AR inhibitors other finastreide and dutasteride


#1

Why are 5 AR inhibitors other than finastreide or dutasteride not popular?
For eg… turosteride


#2

Because they have no side effects.


#3

» Why are 5 AR inhibitors other than finastreide or dutasteride not popular?
» For eg… turosteride

They’re not popular because they’re not available.

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#4

But why pharmaceutical companies not trying to market them?

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» They’re not popular because they’re not available.
»
» .


#5

» But why pharmaceutical companies not trying to market them?

Because we already have finasteride and dutasteride. Nobody wants to spend millions of $$$ for FDA approval just to re-invent the wheel.

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#6

It seems to me that there would be no reason for developing any more of these things just to inhibit DHT.

Finasteride already targets DHT#2 about as well as anything probably ever will. And the side effects are the result of the drug’s primary effect, so I see little hope of sidestepping them with any variations on the drug action.