WNT-Act is the first product to attack hair loss at the gene level by upregulating WNT and downregulating DKK1. Like all the goods that interfere with hair loss, no product is going to reverse hair loss completely. No product is going to retard hair loss completely. Combinations of products may be more beneficial than one alone. WNT-Act is a topical, plant based product studied by Antonella Tosti at the University of Miami. Dr. Tosti is a world renowned researcher, particularly in hair loss. She studied this product in women and found a positive influence in hair mass. WNT-Act is one of the few products that seems to work in women.
I would upload the study, but I have it in PDF format. Let me see if we can build a link to the study.
We do not produce this product. We believe in this product, so we act as distributors of the product. We believe in the product because there is science behind the product. This not a panacea. WNT-Act is a crutch. An all natural crutch. The WNT pathway is well known to promote hair growth. Methyl Vanillate increased WNT by 32% in Dr. Tosti’s study.
Briefly, the Tosti study included 20 women over a 6-month trial. She saw an increase in hair mass between 6% to 12% over that period. Now, compare this to PRP. Standard PRP does not increase hair mass over a 6-month span of time. Only sonicated PRP or platelet lysate can increase hair mass at six months and nearly by 100% in some patients. When you compare the cost of everything, WNT-Act is inexpensive compared to sonicated PRP, but I suspect they are additive. With sonicated PRP at 6-months, we have seen hair density increase from 90 hairs per square cm to 200 hair per square cm, and we have seen follicular density increase from 60 per square cm to 90 per square cm.
I do not believe there is a product that will work positively for all individuals. Sometimes, multiple products work better than a single product.
When you look at high-quality regular PRP, you can see a 50% increase int hair density at six months, but no increase in the hair mass. Poorer quality standard PRP produces a 25% decrease in hair density at six months and again no increase in hair mass. Thus, don’t just sign up for PRP. Remember, very few doctors study their results. You must be careful. Only sonicated PRP or platelet lysate or cytokine-rich plasma with 5 to 8 times the concentration of growth factors increases hair mass, by significant margins in some, at six months.
A positive change in hair mass is a reason I’m very excited about WNT-Act. This product increased hair mass by 6-12% at six months. We don’t set the pricing. The manufacturer does. However, when you compare the price to the benefit, especially in comparison to standard PRP, and you don’t need to leave your home to gain the benefits, the cost begins to look reasonable.
I believe enough in the product to discount WNT-Act to my patients, and I eat the difference.