And I'm starting to think that this Tregs cell discovery shows us the reason that so many hair loss treatments don't work very well, and why so much advanced research hasn't panned out into a cure. An effective hair loss treatment or cure for MPB will have to either directly address the Tregs cells issue, or act upstream of it to ensure that Tregs cells aren't suppressed.
Aderans, Intercytex, Gho, etc. had very limited success and the first two failed and shut down trials, while the latter worked for years and got nowhere, because they all attacked the problem with a cell-based approach, but didn't address Tregs cells (of course they couldn't have known about the importance of Tregs cells when they were running their trials.)
Replicel/Shiseido and others, are also specifically using cell replacement technologies (stem cells or DP cells), but likewise, they are NOT addressing the Tregs cells issue. So, they're not likely to be very successful either, IMO, unless they figure out how to repopulate the tissue surrounding the follicles with Tregs cells.